Pathogenic Mechanisms of Collagen TypeⅦA1 (COL7A1) and Transporter Protein Transport and Golgi Organization 1 (TANGO1) in Rheumatoid Arthritis: A New Therapeutic Target

Pathogenic Mechanisms of Collagen TypeⅦA1 (COL7A1) and Transporter Protein Transport and Golgi Organization 1 (TANGO1) in Rheumatoid Arthritis: A New Therapeutic Target

Rheumatoid arthritis (RA) is an autoimmune disorder causing chronic inflammation primarily due to collagen regulation and transport imbalances. Collagen VII A1(COL7A1), a major component of anchoring fibrils, regulates inflammation via interacting with its transporter protein Transport and Golgi org...

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Bibliographic Details
Main Authors: Debolina Chakraborty, Prachi Agnihotri, Lovely Joshi, Mohd Saquib, Swati Malik, Uma Kumar, Sagarika Biswas
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Immuno
Subjects:
rheumatoid arthritis
COL7A1
TANGO1
therapeutic drugs
inflammation
Online Access:https://www.mdpi.com/2673-5601/4/4/29
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