The Derivative Difluoroboranyl-Fluoroquinolone “7a” Generates Effective Inhibition Against the <i>S. aureus</i> Strain in a Murine Model of Acute Pneumonia

The Derivative Difluoroboranyl-Fluoroquinolone “7a” Generates Effective Inhibition Against the <i>S. aureus</i> Strain in a Murine Model of Acute Pneumonia

During the last decades, most bacterial strains have become increasingly resistant to antibiotics. This led the WHO to declare a global emergency in 2017 and urge the development of new active compounds. Some families of antibiotics still show high antibacterial efficacy, as is the case of fluoroqui...

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Bibliographic Details
Main Authors: L. Angel Veyna-Hurtado, Hiram Hernández-López, Fuensanta del Rocío Reyes-Escobedo, Denisse de Loera, Salvador García-Cruz, Lorena Troncoso-Vázquez, Marisol Galván-Valencia, Julio E. Castañeda-Delgado, Alberto Rafael Cervantes-Villagrana
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Current Issues in Molecular Biology
Subjects:
fluoroquinolone
<i>S. aureus</i>
antimicrobial
molecular docking
pneumonia
histopathology
Online Access:https://www.mdpi.com/1467-3045/47/2/110
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