Helicobacter pylori infection and staple-line leak in patients with class III obesity undergoing laparoscopic sleeve gastrectomy: a retrospective study
Objective Globally, over 50% of the population is affected by Helicobacter pylori, yet research on its prevalence and impact in patients with obesity undergoing laparoscopic sleeve gastrectomy (LSG) is inconclusive. This study aimed to assess the prevalence of H. pylori infection in individuals with...
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BMJ Publishing Group
2024-12-01
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| Series: | BMJ Open Gastroenterology |
| Online Access: | https://bmjopengastro.bmj.com/content/11/1/e001622.full |
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| author | Hani Tamim Albaraa H Kazim Fahad Y Bamehriz Aldanah M Althwanay Abdullah Aldohayan Al-Bandari Zamil Abdullah Bandar AlShehri Rakan Masoud AlTuwayr Habeeb I A Razack Fahad Alsohaibani Saleh A Alqahtani |
| author_facet | Hani Tamim Albaraa H Kazim Fahad Y Bamehriz Aldanah M Althwanay Abdullah Aldohayan Al-Bandari Zamil Abdullah Bandar AlShehri Rakan Masoud AlTuwayr Habeeb I A Razack Fahad Alsohaibani Saleh A Alqahtani |
| author_sort | Hani Tamim |
| collection | DOAJ |
| description | Objective Globally, over 50% of the population is affected by Helicobacter pylori, yet research on its prevalence and impact in patients with obesity undergoing laparoscopic sleeve gastrectomy (LSG) is inconclusive. This study aimed to assess the prevalence of H. pylori infection in individuals with obesity undergoing LSG, evaluate the percentage of postoperative staple-line leaks, and explore the potential link between H. pylori infection and staple-line leaks.Methods This retrospective analysis assessed adult patients with class III obesity who underwent LSG between 2015 and 2020 at a tertiary care hospital in Riyadh, Saudi Arabia. Patient characteristics with and without postoperative staple-line leaks were compared, exploring the link between H. pylori infection and these leaks.Results Of the 2099 patients (mean age, 34.7±12.2 years; female, 53.5%) included, 35% had H. pylori infection and 2% experienced post-LSG staple-line leaks. Patients with H. pylori were older (36.1±11.8 vs 34.0±12.3 years, p<0.0001). Patients with leaks were older, mostly male, and had higher body mass index (p<0.05). However, only 29% of those with leaks were H. pylori-positive. A non-significant association was found between H. pylori infection and staple-line leaks (adjusted OR 0.73, 95% CI 0.33 to 1.60, accounting for age, body mass index, and sex).Conclusions Although over one-third of patients with class III obesity undergoing LSG had H. pylori infection, a non-significant association was observed with post-LSG staple-line leaks, suggesting routine preoperative H. pylori screening may not be necessary. |
| format | Article |
| id | doaj-art-65adf7cca9d34cfc97213a4aa0f8903b |
| institution | Kabale University |
| issn | 2054-4774 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open Gastroenterology |
| spelling | doaj-art-65adf7cca9d34cfc97213a4aa0f8903b2025-01-14T21:35:14ZengBMJ Publishing GroupBMJ Open Gastroenterology2054-47742024-12-0111110.1136/bmjgast-2024-001622Helicobacter pylori infection and staple-line leak in patients with class III obesity undergoing laparoscopic sleeve gastrectomy: a retrospective studyHani Tamim0Albaraa H Kazim1Fahad Y Bamehriz2Aldanah M Althwanay3Abdullah Aldohayan4Al-Bandari Zamil Abdullah5Bandar AlShehri6Rakan Masoud AlTuwayr7Habeeb I A Razack8Fahad Alsohaibani9Saleh A Alqahtani10College of Medicine, Alfaisal University, Riyadh, Saudi ArabiaBariatric and Upper Gastro-Intestinal Surgery Unit, College of Medicine, King Saud University, Riyadh, Saudi ArabiaBariatric and Upper Gastro-Intestinal Surgery Unit, College of Medicine, King Saud University, Riyadh, Saudi ArabiaDivision of Gastroenterology and Hepatology, Washington University at St. Louis, St. Louis, MO, USASurgery Division, King Khalid University Hospital, King Saud University, Riyadh, Saudi ArabiaAlHabib Medical Group Hospital, Riyadh, Saudi ArabiaDiabetes and Endocrinology, Faculty of Medicine, University of Jeddah, Jeddah, Saudi ArabiaGeneral Surgery Department, Al-Iman General Hospital, Riyadh, Saudi ArabiaCollege of Medicine, King Saud University, Riyadh, Saudi ArabiaDepartment of Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi ArabiaDivision of Gastroenterology & Hepatology, Weill Cornell Medicine, New York, New York, USAObjective Globally, over 50% of the population is affected by Helicobacter pylori, yet research on its prevalence and impact in patients with obesity undergoing laparoscopic sleeve gastrectomy (LSG) is inconclusive. This study aimed to assess the prevalence of H. pylori infection in individuals with obesity undergoing LSG, evaluate the percentage of postoperative staple-line leaks, and explore the potential link between H. pylori infection and staple-line leaks.Methods This retrospective analysis assessed adult patients with class III obesity who underwent LSG between 2015 and 2020 at a tertiary care hospital in Riyadh, Saudi Arabia. Patient characteristics with and without postoperative staple-line leaks were compared, exploring the link between H. pylori infection and these leaks.Results Of the 2099 patients (mean age, 34.7±12.2 years; female, 53.5%) included, 35% had H. pylori infection and 2% experienced post-LSG staple-line leaks. Patients with H. pylori were older (36.1±11.8 vs 34.0±12.3 years, p<0.0001). Patients with leaks were older, mostly male, and had higher body mass index (p<0.05). However, only 29% of those with leaks were H. pylori-positive. A non-significant association was found between H. pylori infection and staple-line leaks (adjusted OR 0.73, 95% CI 0.33 to 1.60, accounting for age, body mass index, and sex).Conclusions Although over one-third of patients with class III obesity undergoing LSG had H. pylori infection, a non-significant association was observed with post-LSG staple-line leaks, suggesting routine preoperative H. pylori screening may not be necessary.https://bmjopengastro.bmj.com/content/11/1/e001622.full |
| spellingShingle | Hani Tamim Albaraa H Kazim Fahad Y Bamehriz Aldanah M Althwanay Abdullah Aldohayan Al-Bandari Zamil Abdullah Bandar AlShehri Rakan Masoud AlTuwayr Habeeb I A Razack Fahad Alsohaibani Saleh A Alqahtani Helicobacter pylori infection and staple-line leak in patients with class III obesity undergoing laparoscopic sleeve gastrectomy: a retrospective study BMJ Open Gastroenterology |
| title | Helicobacter pylori infection and staple-line leak in patients with class III obesity undergoing laparoscopic sleeve gastrectomy: a retrospective study |
| title_full | Helicobacter pylori infection and staple-line leak in patients with class III obesity undergoing laparoscopic sleeve gastrectomy: a retrospective study |
| title_fullStr | Helicobacter pylori infection and staple-line leak in patients with class III obesity undergoing laparoscopic sleeve gastrectomy: a retrospective study |
| title_full_unstemmed | Helicobacter pylori infection and staple-line leak in patients with class III obesity undergoing laparoscopic sleeve gastrectomy: a retrospective study |
| title_short | Helicobacter pylori infection and staple-line leak in patients with class III obesity undergoing laparoscopic sleeve gastrectomy: a retrospective study |
| title_sort | helicobacter pylori infection and staple line leak in patients with class iii obesity undergoing laparoscopic sleeve gastrectomy a retrospective study |
| url | https://bmjopengastro.bmj.com/content/11/1/e001622.full |
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