Rapid and sensitive detection of Haemophilus influenzae using multiple cross displacement amplification combined with CRISPR-Cas12a-based biosensing system

Rapid and sensitive detection of Haemophilus influenzae using multiple cross displacement amplification combined with CRISPR-Cas12a-based biosensing system

Haemophilus influenzae (H. influenzae, Hi) is an opportunistic bacterium that colonizes the upper respiratory tract of humans and frequently causes meningitis, pneumonia, sepsis, and other severe infections in children. Early and accurate detection of H. influenzae is essential for effective diagnos...

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Bibliographic Details
Main Authors: Xinbei Jia, Wenjian Xu, Fei Xiao, Nan Jia, Xiaolan Huang, Yiqin Zhang, Juan Zhou, Yi Wang, Jun Tai
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Heliyon
Subjects:
Haemophilus influenzae
CRISPR-Cas12a
Multiple cross displacement amplification
MCDA
Outer membrane protein P6
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024175664
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