Checkpoint inhibitor-expressing lentiviral vaccine suppresses tumor growth in preclinical cancer models

Background While immunotherapy has been highly successful for the treatment of some cancers, for others, the immune response to tumor antigens is weak leading to treatment failure. The resistance of tumors to checkpoint inhibitor therapy may be caused by T cell exhaustion resulting from checkpoint a...

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Bibliographic Details
Main Authors: Thomas D Norton, Takuya Tada, Rebecca Leibowitz, Nathaniel R Landau
Format: Article
Language:English
Published: BMJ Publishing Group 2024-04-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/12/4/e008761.full
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