Role of Nicotinamide in the Pathogenesis of Actinic Keratosis: Implications for NAD<sup>+</sup>/SIRT1 Pathway

Role of Nicotinamide in the Pathogenesis of Actinic Keratosis: Implications for NAD<sup>+</sup>/SIRT1 Pathway

Actinic keratosis (AK) is a precursor to invasive squamous cell carcinoma, making early diagnosis and treatment essential to prevent progression. Among available therapeutic options, nicotinamide (NAM) has shown potential in reducing AK progression. NAM is a precursor of nicotinamide adenine dinucle...

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Main Authors: Riccardo Belardi, Francesca Pacifici, Terenzio Cosio, Sara Lambiase, Ruslana Gaeta Shumak, Fabio Artosi, Antonia Rivieccio, Danilo Cavalloro, Elena Dellambra, Luca Bianchi, David Della-Morte, Elena Campione
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biomolecules
Subjects:
sirtuin 1 activity
actinic keratosis
NAD<sup>+</sup>
Online Access:https://www.mdpi.com/2218-273X/14/12/1512
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