Empagliflozin alleviates type 2 diabetic renal fibrosis by inhibiting SLC7A7-mediated ferroptosis

Abstract Background Diabetic Kidney Disease (DKD) represents the most prevalent secondary kidney condition that progresses to end-stage renal disease globally. Empagliflozin (EMPA) effectively reduce blood glucose levels to mitigate the impact of DKD. Methods Researchers extracted kidney tissues fro...

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Bibliographic Details
Main Authors: Wendi Zhao, Guoxi Jin, Weihua Sun, Chenchen Wu, Qingqing Yang, Li Xue, Shandong Ye
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Diabetology & Metabolic Syndrome
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Online Access:https://doi.org/10.1186/s13098-025-01902-6
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