Tangeretin inhibits airway inflammatory responses by reducing early growth response 1 (EGR1) expression in mice exposed to cigarette smoke and lipopolysaccharide

Tangeretin inhibits airway inflammatory responses by reducing early growth response 1 (EGR1) expression in mice exposed to cigarette smoke and lipopolysaccharide

Background: Tangeretin, a natural polymethoxyflavone compound, possesses potent anti-inflammatory activity that improves respiratory inflammation in chronic obstructive pulmonary disease (COPD). However, the molecular mechanisms underlying the anti-COPD effects of tangeretin remain unclear. In this...

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Bibliographic Details
Main Authors: Eun Sol Oh, Jae-Won Lee, Yu Na Song, Mun-Ock Kim, Ro Woon Lee, Myung-Ji Kang, Juhyun Lee, Seok Han Yun, Sung-Tae Hong, Hyunju Ro, Su Ui Lee
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Heliyon
Subjects:
Chronic obstructive pulmonary disease
Cigarette smoke
EGR1
Human lung epithelial cell
MUC5AC
Tangeretin
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024158288
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