CXCL12α/SDF‐1 from perisynaptic Schwann cells promotes regeneration of injured motor axon terminals
Abstract The neuromuscular junction has retained through evolution the capacity to regenerate after damage, but little is known on the inter‐cellular signals involved in its functional recovery from trauma, autoimmune attacks, or neurotoxins. We report here that CXCL12α, also abbreviated as stromal‐...
Saved in:
| Main Authors: | Samuele Negro, Francesca Lessi, Elisa Duregotti, Paolo Aretini, Marco La Ferla, Sara Franceschi, Michele Menicagli, Elisanna Bergamin, Egle Radice, Marcus Thelen, Aram Megighian, Marco Pirazzini, Chiara M Mazzanti, Michela Rigoni, Cesare Montecucco |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2017-05-01
|
| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.201607257 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Tissue Stem Cell-Based Therapies in Parkinson’s Disease: A Scoping Review of Therapeutic Mechanisms and Translational Outcomes
by: Emily Cueva, et al.
Published: (2025-06-01) -
Plasmalogen as a Bioactive Lipid Drug: From Preclinical Research Challenges to Opportunities in Nanomedicine
by: Yu Wu, et al.
Published: (2025-08-01) -
Perisynaptic GABA Receptors: The Overzealous Protector
by: Andrew N. Clarkson
Published: (2012-01-01) -
ROLE OF SCHWANN CELLS-CANCER CELLS CROSSTALK IN TUMOUR PROGRESSION
Published: (2025-08-01) -
Schwann cells modified to secrete MANF is a potential cellular therapy for peripheral nerve regeneration
by: Bhadrapriya Sivakumar, et al.
Published: (2025-07-01)