Analysis of the progression of cervical cancer in a low-and-middle-income country: From pre-malignancy to invasive disease

Analysis of the progression of cervical cancer in a low-and-middle-income country: From pre-malignancy to invasive disease

To better understand cervical cancer progression, we analyzed RNA from 262 biopsies from women referred for colposcopy. We determined the HPV type and analyzed the expression of 51 genes. HPV31 was significantly more prevalent in precancer than stage 1 cancer and invasive cancer (p < 0.0001), and...

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Main Authors: Emma Robinson, Isabel Rodriguez, Victor Argueta, Yi Xie, Hong Lou, Rose Milano, Hyo Jung Lee, Laurie Burdett, Sambit K. Mishra, Meredith Yeager, Lisa Mirabello, Michael Dean, Roberto Orozco
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Tumour Virus Research
Subjects:
Cervical cancer
Precancer
Gene expression
Tumor microenvironment
Human papillomavirus
Cancer progression
Online Access:http://www.sciencedirect.com/science/article/pii/S2666679024000235
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