Exploring diagnostic m6A regulators in primary open-angle glaucoma: insight from gene signature and possible mechanisms by which key genes function

Exploring diagnostic m6A regulators in primary open-angle glaucoma: insight from gene signature and possible mechanisms by which key genes function

Abstract Purpose The purpose of this study was to interrogate the potential role of N6-methyladenosine (m6A) regulators in the process of trabecular meshwork (TM) tissue damage in patients with primary open-angle glaucoma (POAG). Methods Firstly, the expression profile of m6A regulators in TM tissue...

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Bibliographic Details
Main Authors: Xinyue Zhang, Jiawei Chen, Xiaoyu Zhou, Dengming Zhou, Li Liao, Yang Zhao, Ping Wu, Fen Nie, Zhimin Liao, Ziyan Cai, Xuanchu Duan
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Medical Genomics
Subjects:
Glaucoma
POAG
N6-methyladenosine
Trabecular meshwork
Oxidative stress
Online Access:https://doi.org/10.1186/s12920-025-02123-6
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https://doi.org/10.1186/s12920-025-02123-6

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