Imaging the uptake and metabolism of glutamine in prostate tumor models using CEST MRI

Imaging the uptake and metabolism of glutamine in prostate tumor models using CEST MRI

Abstract Glutamine metabolism is upregulated in many cancers. While multiple glutamine imaging agents have been developed and translated to clinical use, the short half-lives of their signal and instability in vivo limit the aspects of glutamine metabolism they capture. In phantoms at physiological...

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Main Authors: Yuki Hodo, Caitlin M. Tressler, Behnaz Ghaemi, Rebecca Thomas, Aliyah S. Webster, Kirsten N. Bains Williams, Yuguo Li, Martin G. Pomper, Chi V. Dang, Zaver M. Bhujwalla, Jeff W. M. Bulte, Peter C. M. van Zijl, Aline M. Thomas
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:npj Imaging
Online Access:https://doi.org/10.1038/s44303-025-00100-3
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https://doi.org/10.1038/s44303-025-00100-3

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