Activation of receptor-independent fluid-phase pinocytosis promotes foamy monocyte formation in atherosclerotic mice

Activation of receptor-independent fluid-phase pinocytosis promotes foamy monocyte formation in atherosclerotic mice

Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death worldwide. Clinical and experimental data demonstrated that circulating monocytes internalize plasma lipoproteins and become lipid-laden foamy cells in hypercholesterolemic subjects. This study was designed to identify the...

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Bibliographic Details
Main Authors: WonMo Ahn, Faith N. Burnett, Kamila Wojnar-Lason, Jaser Doja, Amritha Sreekumar, Pushpankur Ghoshal, Bhupesh Singla, Graydon Gonsalvez, Ryan A. Harris, Xiaoling Wang, Joseph M. Miano, Gábor Csányi
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Redox Biology
Subjects:
Monocyte
Macropinocytosis
nLDL
Ox-LDL
Hypercholesterolemia
Atherosclerosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231724004014
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