LncRNA GClnc1 promotes osteosarcoma progression by stabilizing NONO and blocking FBXW7-mediated ubiquitination

LncRNA GClnc1 promotes osteosarcoma progression by stabilizing NONO and blocking FBXW7-mediated ubiquitination

Abstract Background Long non-coding RNA (lncRNA) plays a vital role in the occurrence and development of varieties of tumors. Previous studies have shown that lncRNA GClnc1 is highly expressed in osteosarcoma (OS). However, the mechanism of lncRNA GClnc1 in osteosarcoma has not been fully elucidated...

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Main Authors: Jiongfeng Zhang, Xiaohui Luo, Chong Guo, Zhengzai Dai, Xiaofeng Tang, Feifei Zhang, Quanhui Jiao, Shifan Lin, Le Zou, Zhiping Zhang, Xiao-Bin Lv
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Cancer
Subjects:
Osteosarcoma
LncRNA GClnc1
NONO
Migration and invasion
Proliferation
Online Access:https://doi.org/10.1186/s12885-024-13138-0
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https://doi.org/10.1186/s12885-024-13138-0

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