Honokiol induces apoptosis and autophagy in dexamethasone-resistant T-acute lymphoblastic leukemia CEM-C1 cells

Honokiol induces apoptosis and autophagy in dexamethasone-resistant T-acute lymphoblastic leukemia CEM-C1 cells

Objective: To study whether and, if so, how honokiol overcome dexamethasone resistance in DEX-resistant CEM-C1 cells. Methods: We investigated the effect of honokiol (0–20 µM) on cell proliferation, cell cycle, cell apoptosis and autophagy in DEX-resistant CEM-C1 cells and DEX-sensitive CEM-C7 cells...

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Bibliographic Details
Main Authors: Yang Liu, Suqian Zhang, Yajuan Tan
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Hematology
Subjects:
T-acute lymphoblastic leukemia
dexamethasone-resistance
honokiol
gene c-Myc
BCL-2
cell apoptosis
Online Access:https://www.tandfonline.com/doi/10.1080/16078454.2024.2337307
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https://www.tandfonline.com/doi/10.1080/16078454.2024.2337307

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