Irisin-regulated lncRNAs and their potential regulatory functions in chondrogenic differentiation of human mesenchymal stem cells

Irisin-regulated lncRNAs and their potential regulatory functions in chondrogenic differentiation of human mesenchymal stem cells

Dysregulation of chondrogenic differentiation is associated with osteoarthritis (OA). The myokine irisin is beneficial in OA treatment; yet, the underlying mechanism is not fully understood. Long noncoding RNAs (lncRNAs) act as important regulators of chondrocyte differentiation. This study was cond...

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Bibliographic Details
Main Authors: Chen Yijie, Sha Wenqi, Zhang Yifan, Kou Wanyi, Yang Liu, Guo Ruixin, Li Chenyang, Zhao Junjie, Wang Zhenghui
Format: Article
Language:English
Published: De Gruyter 2024-11-01
Series:Open Medicine
Subjects:
irisin
chondrogenic differentiation
lncrnas
co-expression
cernas
Online Access:https://doi.org/10.1515/med-2024-1073
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https://doi.org/10.1515/med-2024-1073

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