Synthesis and Characterization of Two Sparfloxacin Crystalline Salts: Enhancing Solubility and In Vitro Antibacterial Activity of Sparfloxacin

Synthesis and Characterization of Two Sparfloxacin Crystalline Salts: Enhancing Solubility and In Vitro Antibacterial Activity of Sparfloxacin

<b>Background</b>: To improve the solubility and permeability of Sparfloxacin (SPX) and enhance its antimicrobial activity in vitro, two unreported pharmaceutical crystalline salts were synthesized and characterized in this paper. One is a hydrated crystal of Sparfloxacin with Pimelic ac...

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Bibliographic Details
Main Authors:	Wei Sun, Ruili Huo, Jingzhong Duan, Jixiang Xiao, Yan Wang, Xiaoping Zhou
Format:	Article
Language:	English
Published:	MDPI AG 2024-11-01
Series:	Pharmaceutics
Subjects:	sparfloxacin crystalline salts pimelic acid azelaic acid solubility antimicrobial activity
Online Access:	https://www.mdpi.com/1999-4923/16/12/1519
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