Synthesis and Characterization of Two Sparfloxacin Crystalline Salts: Enhancing Solubility and In Vitro Antibacterial Activity of Sparfloxacin

<b>Background</b>: To improve the solubility and permeability of Sparfloxacin (SPX) and enhance its antimicrobial activity in vitro, two unreported pharmaceutical crystalline salts were synthesized and characterized in this paper. One is a hydrated crystal of Sparfloxacin with Pimelic ac...

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Bibliographic Details
Main Authors: Wei Sun, Ruili Huo, Jingzhong Duan, Jixiang Xiao, Yan Wang, Xiaoping Zhou
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pharmaceutics
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Online Access:https://www.mdpi.com/1999-4923/16/12/1519
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