One step derivatization and switchable hydrophilicity solvent-based microextraction for the determination of adamantane analogues in human urine by HPLC-FLD

The present study describes an “one-step” derivatization and microextraction using a pH-switchable hydrophilicity solvent for the determination of amantadine and memantine in human urine by liquid chromatography and fluorescence detection. The procedure is based on the derivatization of the analytes...

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Bibliographic Details
Main Authors: Marianna Ntorkou, Paraskevas D. Tzanavaras, Constantinos K. Zacharis
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Advances in Sample Preparation
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Online Access:http://www.sciencedirect.com/science/article/pii/S2772582024000330
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