Temporal ablation of the ciliary protein IFT88 alters normal brainwave patterns

Abstract The primary cilium is a hair-like organelle that hosts molecular machinery for various developmental and homeostatic signaling pathways. Its alteration can cause rare ciliopathies such as the Bardet-Biedl and Joubert syndromes, but is also linked to Alzheimer’s disease, clinical depression,...

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Bibliographic Details
Main Authors: Matthew R. Strobel, Yuxin Zhou, Liyan Qiu, Aldebaran M. Hofer, Xuanmao Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-024-83432-1
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