M2 Macrophage‐Derived sEV Regulate Pro‐Inflammatory CCR2+ Macrophage Subpopulations to Favor Post‐AMI Cardiac Repair
Abstract Tissue‐resident cardiac macrophage subsets mediate cardiac tissue inflammation and repair after acute myocardial infarction (AMI). CC chemokine receptor 2 (CCR2)‐expressing macrophages have phenotypical similarities to M1‐polarized macrophages, are pro‐inflammatory, and recruit CCR2+ circul...
Saved in:
| Main Authors: | Lan Li, Jiasong Cao, Sheng Li, Tianyi Cui, Jingyu Ni, Han Zhang, Yan Zhu, Jingyuan Mao, Xiumei Gao, Adam C. Midgley, Meifeng Zhu, Guanwei Fan |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-05-01
|
| Series: | Advanced Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/advs.202202964 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Research advances of CCR2/MCP-1 and kidney diseases
by: Shen Yan-jie, et al.
Published: (2021-01-01) -
Effects of mesenchymal stromal cells on monocyte differentiation to M1 phenotype and M1/M2 macrophage switching
by: E. Ya. Shevela, et al.
Published: (2018-03-01) -
Macrophages and fibroblasts in cardiac fibrosis: interactions and transformation
by: Daehun Kim, et al.
Published: (2025-08-01) -
Macrophages and tumor progression: on the way to macrophage-specific therapy
by: N. V. Cherdyntseva, et al.
Published: (2018-01-01) -
Tumor‐associated macrophages‐educated reparative macrophages promote diabetic wound healing
by: Ruoyu Mu, et al.
Published: (2022-12-01)