TIGAR regulated by HPV E6 is correlated with disease stage, drug sensitivity, and immune microenvironment in cervical cancer

TIGAR regulated by HPV E6 is correlated with disease stage, drug sensitivity, and immune microenvironment in cervical cancer

Abstract Cervical cancer is the fourth most common malignant tumor in women, lacking specific and sensitive markers. TP53 induced glycolysis regulatory phosphatase (TIGAR) plays an important role in the initiation and progression of several solid tumors. This study aims to investigate the diagnostic...

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Bibliographic Details
Main Authors: Yameng Liu, Yu Zhang, Hailong Zhang, Dianqin Xu, Xinzhu Zhou, Luhong Xie, Hongli Xi, Yurong Zhu, Hanlin Yang, Xiaoyu Zhu, Ji Ren, Shaoju Min, Yujie Tan
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
TIGAR
Immune infiltration
Tumor immunosuppressive microenvironment
Cervical cancer
Prognosis
Online Access:https://doi.org/10.1038/s41598-025-07201-4
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https://doi.org/10.1038/s41598-025-07201-4

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