Development of an inhalable contrast agent targeting the respiratory tract mucus layer for pulmonary ultrasonic imaging

Development of an inhalable contrast agent targeting the respiratory tract mucus layer for pulmonary ultrasonic imaging

Abstract Impaired mucociliary transport is a distinguishing sign of cystic fibrosis, but current methods of evaluation are invasive or expose young patients to ionizing radiation. Contrast-enhanced ultrasound imaging may provide a feasible alternative. We formulated a cationic microbubble ultrasound...

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Main Authors: James K. Tsuruta, Patrick R. Sears, Meghan E. Rebuli, Andrew S. Weitz, Phillip G. Durham, Phillip W. Clapp, David B. Hill, Lawrence E. Ostrowski, Paul A. Dayton, Melissa C. Caughey
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Ultrasound
Contrast agent
Microbubble
Pulmonary
Mucociliary transport
Cystic fibrosis
Online Access:https://doi.org/10.1038/s41598-024-80933-x
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https://doi.org/10.1038/s41598-024-80933-x

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