Triage test for all-oral drug-resistant tuberculosis (DR-TB) regimen: a phase IV study to assess effectiveness, feasibility, acceptability and cost-effectiveness of the Xpert MTB/XDR assay for rapid triage and treatment of DR-TB

Triage test for all-oral drug-resistant tuberculosis (DR-TB) regimen: a phase IV study to assess effectiveness, feasibility, acceptability and cost-effectiveness of the Xpert MTB/XDR assay for rapid triage and treatment of DR-TB

Introduction The TriAD study will assess the Xpert MTB/XDR (Xpert XDR; Cepheid) assay to detect tuberculosis (TB) drug resistance in sputum testing positive for TB to rapidly triage and treat patients with a short all-oral treatment regimen.Methods and analysis In this study, approximately 4800 Xper...

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Main Authors: Kogieleum Naidoo, Derek J Sloan, Wilber Sabiiti, Bariki Mtafya, Stephen H Gillespie, Aderonke Agbaje, Nyanda Elias Ntinginya, Morten Ruhwald, Agnes Gebhard, Anushka Naidoo, Rubeshan Perumal, Getachew Tollera, Evaezi Okpokoro, Alash'le G Abimiku, Everdina W Tiemersma, Sabine M Hermans, Sophia B Georghiou, Kalkidan Yae, Shewki Moga, Hannelise Feyt, Takondwa Kachoka, Marothi P Letsoalo, Andrea M Cabibbe, Letitia Shunmugam, Daniela M Cirillo, Salah Foraida
Format: Article
Language:English
Published: BMJ Publishing Group 2024-11-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/14/11/e084722.full
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https://bmjopen.bmj.com/content/14/11/e084722.full

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