Moderating role of triglycerides in the relationship between amyloid-β, hippocampal atrophy, and cognitive decline in mild cognitive impairment and early Alzheimer’s disease

Moderating role of triglycerides in the relationship between amyloid-β, hippocampal atrophy, and cognitive decline in mild cognitive impairment and early Alzheimer’s disease

IntroductionThe role of triglycerides in Alzheimer’s disease dementia (ADD) progression remains unclear. This study aimed to investigate how triglyceride levels influence the relationship between amyloid-beta (Aβ) deposition, hippocampal atrophy, and cognitive decline in individuals with mild cognit...

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Bibliographic Details
Main Authors: Ji-Woo Seok, Kahye Kim, Soonjo Hwang, Kun Ho Lee, Jaeuk U. Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Aging Neuroscience
Subjects:
triglycerides
amyloid-beta deposition
hippocampal atrophy
cognitive decline
moderated mediation
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2025.1592341/full
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https://www.frontiersin.org/articles/10.3389/fnagi.2025.1592341/full

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