Contribution of efflux pump hyperactivity to the resistance to new β-lactam-β-lactamase inhibitor combinations including ceftazidime-avibactam, aztreonam-avibactam, and imipenem-relebactam

Contribution of efflux pump hyperactivity to the resistance to new β-lactam-β-lactamase inhibitor combinations including ceftazidime-avibactam, aztreonam-avibactam, and imipenem-relebactam

AIM: To investigate the resistance mechanisms of new β-lactam-β-lactamase inhibitor (β+βi) combinations in Enterobacterales isolates from Taiwan. BACKGROUND: New β+βi combinations, including ceftazidime-avibactam (CAZ-AVI), aztreonam-avibactam (AZT-AVI), and imipenem-relebactam (IMI-REL), are potent...

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Bibliographic Details
Main Authors: Sung Pin Tseng, Tsung Ying Yang, Pu He, Yu Cin Deng, Po Liang Lu
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
β-lactam-β-lactamase inhibitor combinations
antibiotic resistance
pump hyperactivity
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716524002078
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