Yiqi Juanshen decoction alleviates renal interstitial fibrosis by targeting the LOXL2/PI3K/AKT pathway to suppress EMT and inflammation
Abstract Chronic kidney disease (CKD) is a major health concern, with renal interstitial fibrosis (RIF) as a key feature. Effective management of RIF is crucial for treating CKD. Yiqi Juanshen decoction (YQJSD), as traditional Chinese medicine, has shown promising results in CKD treatment. This stud...
Saved in:
Main Authors: | Kaiyue Tan, Jingwei Deng, Yi Liu, Yudi Zhang, Yu Xiong, Su Yuan, Jun Liu, Zhiwei Chen, Yuanyuan Liu, Wenfu Cao |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-02-01
|
Series: | Scientific Reports |
Subjects: | |
Online Access: | https://doi.org/10.1038/s41598-025-86622-7 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
NUDT21 regulates lysyl oxidase-like 2(LOXL2) to influence ECM protein cross-linking in silica-induced pulmonary fibrosis
by: Lan Peng, et al.
Published: (2025-01-01) -
Loss of phosphatase and tensin homolog (PTEN) increases Lysyl oxidase-like 2 (LOXL2) expression enhancing the growth of fallopian tube epithelial cells as three-dimensional spheroids
by: Angela Russo, et al.
Published: (2025-01-01) -
Non-lethal sonodynamic therapy mitigates hypertensive renal fibrosis through the PI3K/AKT/mTORC1-autophagy pathway
by: DanDan Liu, et al.
Published: (2025-02-01) -
MFAP5 inhibits the malignant progression of endometrial cancer cells in vitro
by: Liang Guanying, et al.
Published: (2024-12-01) -
Desquamative interstitial pneumonia: If there is smoke there is fire
by: Amit Panjwani, et al.
Published: (2023-12-01)