Characterizing transcripts of HIV-1 different substrains using direct RNA sequencing

Characterizing transcripts of HIV-1 different substrains using direct RNA sequencing

Post-transcriptional processing and modification of viral RNA, including alternative splicing, polyadenylation, and methylation, play crucial roles in regulating viral gene expression, enhancing genomic stability, and increasing replication efficiency. These processes have significant implications f...

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Main Authors: Weizhen Li, Yong Huang, Haowen Yuan, Jingwan Han, Zhengyang Li, Aiping Tong, Yating Li, Hanping Li, Yongjian Liu, Lei Jia, Xiaolin Wang, Jingyun Li, Bohan Zhang, Lin Li
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Heliyon
Subjects:
HIV-1 transcripts
Alternative splicing
Polyadenylation
RNA modification
Nanopore direct RNA sequencing
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024155053
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