Impact of Long‐Term Fasting on Skeletal Muscle: Structure, Energy Metabolism and Function Using 31P/1H MRS and MRI

Impact of Long‐Term Fasting on Skeletal Muscle: Structure, Energy Metabolism and Function Using 31P/1H MRS and MRI

ABSTRACT Background Fasting shows promise for public health, but concerns about muscle loss hinder its acceptance, particularly among the elderly. We explored the impact of long‐term fasting (12 days, 250 kcal/day) on muscle structure, metabolism and performance. Methods We prospectively assessed mu...

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Main Authors: Antoine Naëgel, Magalie Viallon, Hélène Ratiney, Thu Nguyen, Benjamin Leporq, Djahid Kennouche, Thomas Grenier, Franziska Grundler, Robin Mesnage, Jean‐Michel Guy, Robin Schultze, Françoise Wilhelmi de Toledo, Pierre Croisille
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
fasting
magnetic resonance imaging (MRI)
magnetic resonance spectroscopy (MRS)
muscle metabolism
muscle strength
substrate utilization
Online Access:https://doi.org/10.1002/jcsm.13773
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https://doi.org/10.1002/jcsm.13773

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