Mild and reversible nephrotoxicity following repeated administration of damnacanthal in nude mice

Damnacanthal was previously shown to be a promising colorectal cancer therapeutic candidate. Its efficacy relied on multiple administrations. This study, therefore, aims to assess the renal toxicity of 20 mg/kg damnacanthal (DAM20) in nude mice following three, seven and 14 repeated administrations....

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Bibliographic Details
Main Authors: Noppanan Kotsaouppara, Thunyatorn Yimsoo, Worapapar Treesuppharat, Jeeraphong Thanongsaksrikul, Potjanee Srimanote
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:Toxicology Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2214750025002069
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