Peripheral nerve-derived CSF1 induces BMP2 expression in macrophages to promote nerve regeneration and wound healing

Abstract The precise mechanisms regulating inflammatory and prorepair macrophages have not been fully elucidated, despite the pivotal role played by innate immunity in wound healing. We first employed a denervation wound model to validate the crosstalk between neurons and macrophages. Compared to no...

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Bibliographic Details
Main Authors: Kai Wang, Binyu Song, Yuhan Zhu, Juanli Dang, Tong Wang, Yajuan Song, Yi Shi, Shuang You, Sijia Li, Zhou Yu, Baoqiang Song
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-024-00379-7
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