Insights into genetic aberrations and signalling pathway interactions in chronic lymphocytic leukemia: from pathogenesis to treatment strategies
Abstract Chronic lymphocytic leukemia (CLL) is prevalent in adults and is characterized by the accumulation of mature B cells in the blood, bone marrow, lymph nodes, and spleens. Recent progress in therapy and the introduction of targeted treatments [inhibitors of Bruton's tyrosine kinase (BTKi...
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Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-12-01
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Series: | Biomarker Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40364-024-00710-w |
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