Methodology for generating chorioallantoic membrane patient-derived xenograft (CAM-PDX) models of pleural mesothelioma and performing preclinical imaging for the translation of cancer studies and drug screening. [version 1; peer review: 2 approved]

Methodology for generating chorioallantoic membrane patient-derived xenograft (CAM-PDX) models of pleural mesothelioma and performing preclinical imaging for the translation of cancer studies and drug screening. [version 1; peer review: 2 approved]

Background Pleural mesothelioma is a cancer of the lung lining associated with asbestos exposure. Platinum/pemetrexed chemotherapy has been used for many years but provides little benefit and, despite recent immunotherapy advances, prognosis remains poor underpinning the need for development of nove...

Full description

Saved in:
Bibliographic Details
Main Authors: Judy M Coulson, Joseph J Sacco, Michael Shackcloth, Alexander Haragan, Doris M Rassl, Harish Poptani, Anne Herrmann, Liam Shaw, Sarah Barnett, Jan Schulze
Format: Article
Language:English
Published: F1000 Research Ltd 2025-05-01
Series:F1000Research
Subjects:
Chorioallantoic membrane
PDX
pleural mesothelioma
3Rs
preclinical model
PET/CT imaging
eng
Online Access:https://f1000research.com/articles/14-481/v1
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://f1000research.com/articles/14-481/v1

Similar Items