Theta-frequency subthalamic stimulation enhances conflict resolution in Parkinson’s disease patients with freezing of gait through frontal cortex modulation

Abstract Freezing of gait (FOG) in Parkinson’s disease (PD) is a debilitating motor symptom linked to executive dysfunction, particularly impaired conflict resolution. However, the underlying neural mechanisms and optimal treatment remain unclear. We assessed conflict resolution using a modified Fla...

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Main Authors: Hutao Xie, Yutong Bai, Yutong Zhuang, Jiansong Huang, Delong Wu, Xin Zhang, Lin Shi, Hua Zhang, Jian Li, Jing Fu, Anchao Yang, Fangang Meng, Quan Zhang, Yin Jiang, Jianguo Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-025-01067-z
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