A simple and efficient algorithm for genome‐wide homozygosity analysis in disease

Abstract Here we propose a simple statistical algorithm for rapidly scoring loci associated with disease or traits due to recessive mutations or deletions using genome‐wide single nucleotide polymorphism genotyping case–control data in unrelated individuals. This algorithm identifies loci by definin...

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Bibliographic Details
Main Authors: Wei Liu, Jinhui Ding, Jesse Raphael Gibbs, Sue Jane Wang, John Hardy, Andrew Singleton
Format: Article
Language:English
Published: Springer Nature 2009-09-01
Series:Molecular Systems Biology
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Online Access:https://doi.org/10.1038/msb.2009.53
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