Plasmid copy number as a modulator in bacterial pathogenesis and antibiotic resistance
Abstract Plasmid copy number (PCN), the average number of plasmids per bacterial cell, links gene dosage to key traits such as host fitness, virulence, antibiotic resistance and evolutionary potential. Although often viewed as static, PCN is a dynamic, regulated trait responsive to environmental cue...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
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| Series: | npj Antimicrobials and Resistance |
| Online Access: | https://doi.org/10.1038/s44259-025-00145-9 |
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