Design of an innovative nanovehicle to enhance brain permeability of a novel 5-HT6 receptor antagonist
An innovative nanovehicle based on lipid nanocapsules (LNC) was designed to facilitate the passage of a new 5-HT6 receptor antagonist, namely PUC-10, through the blood-brain barrier. PUC-10 is a new synthetic N-arylsulfonylindole that has demonstrated potent 5-HT6 receptor antagonist activity, but i...
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Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-12-01
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Series: | International Journal of Pharmaceutics: X |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2590156724000689 |
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