A Population Pharmacokinetic Model to Inform Extension of the Eteplirsen Dosing Regimen Across the Broad DMD Population

ABSTRACT Duchenne muscular dystrophy (DMD) is characterized by progressive, irreversible muscle damage that usually leads to premature death from cardiac or respiratory failure. Eteplirsen is a phosphorodiamidate morpholino oligomer and the first antisense oligonucleotide (ASO) approved for the trea...

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Bibliographic Details
Main Authors: Yogesh Patel, Larry Orogun, Nicole Yocum, Louise R. Rodino‐Klapac, Lilly East
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:CPT: Pharmacometrics & Systems Pharmacology
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Online Access:https://doi.org/10.1002/psp4.70001
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