5-Hydroxymethylcytosine signatures as diagnostic biomarkers for septic cardiomyopathy

5-Hydroxymethylcytosine signatures as diagnostic biomarkers for septic cardiomyopathy

Abstract At present, there are currently no molecular biomarkers for the early diagnosis of sepsis cardiomyopathy (SCM) in clinical practice. This study focuses on an in-depth examination of the DNA hydroxymethylation profiles within plasma extracellular vesicles and explores potential molecular bio...

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Bibliographic Details
Main Authors: Baixin Zhen, Zhiling Zhao, Hangyu Chen, Wen Li, Lei Zhang, Xi Zhu, Qinggang Ge, Jian Lin
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Extracellular vesicle
5-hydroxymethylcytosine (5hmC)
Septic cardiomyopathy
Machine learning
Molecular biomarkers
Online Access:https://doi.org/10.1038/s41598-025-02489-8
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