External validation of precisebreast, a digital prognostic test for predicting breast cancer recurrence, in an early-stage cohort from the Netherlands

External validation of precisebreast, a digital prognostic test for predicting breast cancer recurrence, in an early-stage cohort from the Netherlands

Abstract Background Current clinical guidelines recommend gene expression profiling to guide treatment in early-stage breast cancer. PreciseBreast (PDxBR) is a digital prognostic tool that integrates artificial intelligence (AI)-derived features from hematoxylin and eosin (H&E) slides with clini...

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Main Authors: Pieter J. Westenend, Claudia Meurs, Gerardo Fernandez, Marcel Prastawa, Abishek Sainath Madduri, Aaron Feliz, Juan Carlos Mejias, Alexander Shtabsky, Xiaozhu Zhang, Brandon Veremis, Rebecca DeAngel, Michael J. Donovan
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Breast Cancer Research
Subjects:
Early-stage breast cancer
Digital pathology
Artificial intelligence
Risk stratification
Prognostic model
Recurrence prediction
Online Access:https://doi.org/10.1186/s13058-025-02104-8
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https://doi.org/10.1186/s13058-025-02104-8

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