Metabolomic profile of cerebral tissue after acoustically-mediated blood-brain barrier opening in a healthy rat model: a focus on the contralateral side

Microbubble (MB)-assisted ultrasound (US) is an innovative modality for the non-invasive, targeted, and efficient delivery of therapeutic molecules into the brain. Previously, we reported the first metabolomic signature of blood–brain barrier opening (BBBO) induced by MB-assisted US. In the present...

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Main Authors:	Antoine Presset, Sylvie Bodard, Antoine Lefèvre, Anaïs Millet, Edward Oujagir, Camille Dupuy, Tarik Iazourène, Ayache Bouakaz, Patrick Emond, Jean-Michel Escoffre, Lydie Nadal-Desbarats
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-11-01
Series:	Frontiers in Molecular Neuroscience
Subjects:	blood–brain barrier opening metabolomics brain’s contralateral side amino acid metabolisms compensatory mechanism ultrasound
Online Access:	https://www.frontiersin.org/articles/10.3389/fnmol.2024.1383963/full
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