Metabolomic profile of cerebral tissue after acoustically-mediated blood-brain barrier opening in a healthy rat model: a focus on the contralateral side

Metabolomic profile of cerebral tissue after acoustically-mediated blood-brain barrier opening in a healthy rat model: a focus on the contralateral side

Microbubble (MB)-assisted ultrasound (US) is an innovative modality for the non-invasive, targeted, and efficient delivery of therapeutic molecules into the brain. Previously, we reported the first metabolomic signature of blood–brain barrier opening (BBBO) induced by MB-assisted US. In the present...

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Bibliographic Details
Main Authors: Antoine Presset, Sylvie Bodard, Antoine Lefèvre, Anaïs Millet, Edward Oujagir, Camille Dupuy, Tarik Iazourène, Ayache Bouakaz, Patrick Emond, Jean-Michel Escoffre, Lydie Nadal-Desbarats
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
blood–brain barrier opening
metabolomics
brain’s contralateral side
amino acid metabolisms
compensatory mechanism
ultrasound
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2024.1383963/full
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https://www.frontiersin.org/articles/10.3389/fnmol.2024.1383963/full

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