Characteristics of patients with coronary artery disease and type 2 diabetes mellitus undergoing elective percutaneous coronary intervention
BACKGROUND: Patients with coronary artery disease (CAD) and type 2 diabetes mellitus (T2DM) represent a distinct group at high cardiovascular risk. Up-to-date information on their management in real-world clinical practice may help identify gaps in care. AIM: The work aimed to characterize the cl...
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| Language: | English |
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Concilium Medicum
2025-01-01
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| Series: | КардиоСоматика |
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| Online Access: | https://cardiosomatics.ru/2221-7185/article/viewFile/676532/204318 |
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| author | Anastasiya G. Neeshpapa Victoria N. Karetnikova |
| author_facet | Anastasiya G. Neeshpapa Victoria N. Karetnikova |
| author_sort | Anastasiya G. Neeshpapa |
| collection | DOAJ |
| description | BACKGROUND: Patients with coronary artery disease (CAD) and type 2 diabetes mellitus (T2DM) represent a distinct group at high cardiovascular risk. Up-to-date information on their management in real-world clinical practice may help identify gaps in care.
AIM: The work aimed to characterize the clinical profile of patients with CAD and T2DM, examine associations with cardiovascular risk factors, and evaluate the adequacy of pharmacotherapy.
METHODS: This study included 50 patients who were electively hospitalized for percutaneous coronary intervention (PCI). Sex, age, and clinical history were recorded, along with anthropometric data. Laboratory parameters included total cholesterol, serum creatinine, blood glucose, and glycated hemoglobin levels. Instrumental assessments included left ventricular ejection fraction by echocardiography and the extent of coronary artery lesions by coronary angiography. Based on these data, a patient profile was constructed, and the adequacy of ongoing pharmacotherapy was evaluated by comparison with data from 2022 in Kemerovo.
RESULTS: Pharmacologic therapy at the time of hospitalization was not optimal in all cases: some patients were not receiving drug classes recommended in standard treatment protocols, and inadequate control of key cardiovascular risk factors was observed (as in the previous study). Target levels of total cholesterol were achieved in only 30 patients (60%), and target levels of glycated hemoglobin in only 26%. Active smoking was reported in 48% of patients, and obesity was observed in 68%.
CONCLUSION: Preparing patients with both CAD and T2DM for elective PCI requires a comprehensive approach to risk factor management. Patients with T2DM undergoing elective PCI often do not receive optimal pharmacologic therapy or achieve adequate control of modifiable risk factors, which warrants close attention and timely correction. |
| format | Article |
| id | doaj-art-5c4498ff06964b5ea61d4013db6c577d |
| institution | Kabale University |
| issn | 2221-7185 2658-5707 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Concilium Medicum |
| record_format | Article |
| series | КардиоСоматика |
| spelling | doaj-art-5c4498ff06964b5ea61d4013db6c577d2025-08-20T03:47:03ZengConcilium MedicumКардиоСоматика2221-71852658-57072025-01-0116211512610.17816/CS67653276604Characteristics of patients with coronary artery disease and type 2 diabetes mellitus undergoing elective percutaneous coronary interventionAnastasiya G. Neeshpapa0https://orcid.org/0000-0002-6808-9959Victoria N. Karetnikova1https://orcid.org/0000-0002-9801-9839Research Institute for Complex Issues of Cardiovascular DiseasesResearch Institute for Complex Issues of Cardiovascular DiseasesBACKGROUND: Patients with coronary artery disease (CAD) and type 2 diabetes mellitus (T2DM) represent a distinct group at high cardiovascular risk. Up-to-date information on their management in real-world clinical practice may help identify gaps in care. AIM: The work aimed to characterize the clinical profile of patients with CAD and T2DM, examine associations with cardiovascular risk factors, and evaluate the adequacy of pharmacotherapy. METHODS: This study included 50 patients who were electively hospitalized for percutaneous coronary intervention (PCI). Sex, age, and clinical history were recorded, along with anthropometric data. Laboratory parameters included total cholesterol, serum creatinine, blood glucose, and glycated hemoglobin levels. Instrumental assessments included left ventricular ejection fraction by echocardiography and the extent of coronary artery lesions by coronary angiography. Based on these data, a patient profile was constructed, and the adequacy of ongoing pharmacotherapy was evaluated by comparison with data from 2022 in Kemerovo. RESULTS: Pharmacologic therapy at the time of hospitalization was not optimal in all cases: some patients were not receiving drug classes recommended in standard treatment protocols, and inadequate control of key cardiovascular risk factors was observed (as in the previous study). Target levels of total cholesterol were achieved in only 30 patients (60%), and target levels of glycated hemoglobin in only 26%. Active smoking was reported in 48% of patients, and obesity was observed in 68%. CONCLUSION: Preparing patients with both CAD and T2DM for elective PCI requires a comprehensive approach to risk factor management. Patients with T2DM undergoing elective PCI often do not receive optimal pharmacologic therapy or achieve adequate control of modifiable risk factors, which warrants close attention and timely correction.https://cardiosomatics.ru/2221-7185/article/viewFile/676532/204318coronary artery diseasepercutaneous coronary interventiondiabetes mellitusatherosclerosis |
| spellingShingle | Anastasiya G. Neeshpapa Victoria N. Karetnikova Characteristics of patients with coronary artery disease and type 2 diabetes mellitus undergoing elective percutaneous coronary intervention КардиоСоматика coronary artery disease percutaneous coronary intervention diabetes mellitus atherosclerosis |
| title | Characteristics of patients with coronary artery disease and type 2 diabetes mellitus undergoing elective percutaneous coronary intervention |
| title_full | Characteristics of patients with coronary artery disease and type 2 diabetes mellitus undergoing elective percutaneous coronary intervention |
| title_fullStr | Characteristics of patients with coronary artery disease and type 2 diabetes mellitus undergoing elective percutaneous coronary intervention |
| title_full_unstemmed | Characteristics of patients with coronary artery disease and type 2 diabetes mellitus undergoing elective percutaneous coronary intervention |
| title_short | Characteristics of patients with coronary artery disease and type 2 diabetes mellitus undergoing elective percutaneous coronary intervention |
| title_sort | characteristics of patients with coronary artery disease and type 2 diabetes mellitus undergoing elective percutaneous coronary intervention |
| topic | coronary artery disease percutaneous coronary intervention diabetes mellitus atherosclerosis |
| url | https://cardiosomatics.ru/2221-7185/article/viewFile/676532/204318 |
| work_keys_str_mv | AT anastasiyagneeshpapa characteristicsofpatientswithcoronaryarterydiseaseandtype2diabetesmellitusundergoingelectivepercutaneouscoronaryintervention AT victoriankaretnikova characteristicsofpatientswithcoronaryarterydiseaseandtype2diabetesmellitusundergoingelectivepercutaneouscoronaryintervention |