Nuclear receptors CAR and PXR as cardiometabolic regulators

The constitutive androstane receptor (CAR) and pregnane X receptor (PXR) were initially described as xenobiotic sensors, but an increasing number of studies have linked their activity to other important physiological processes including glucose and lipid metabolism, implying an expanded role as meta...

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Bibliographic Details
Main Authors: Janne Hukkanen, Jenni Küblbeck, Jukka Hakkola, Jaana Rysä
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Pharmacological Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S1043661825003172
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