Does Metamizole Cause Less Acute Kidney Injury than Non-Steroidal Anti-Inflammatory Drugs When Combined with Diuretics and Antihypertensives?

Does Metamizole Cause Less Acute Kidney Injury than Non-Steroidal Anti-Inflammatory Drugs When Combined with Diuretics and Antihypertensives?

The concurrent use of (a) diuretics, (b) renin–angiotensin–aldosterone system inhibitors (RAASIs), and (c) non-steroidal anti-inflammatory drugs (NSAIDs) or metamizole, known as the triple whammy (TW) combination, increases the risk of acute kidney injury (AKI). This study compared TWs including met...

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Bibliographic Details
Main Authors: Dulce Maria Calvo, Luis Carlos Saiz, Leire Leache, Maria C. Celaya, Marta Gutiérrez-Valencia, Alvaro Alonso, Juan Erviti
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Toxics
Subjects:
acute kidney injury
antihypertensives
diuretics
metamizole
non-steroidal anti-inflammatory agents
safety
Online Access:https://www.mdpi.com/2305-6304/13/5/417
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