Distinguishing host responses, extensive viral dissemination and long-term viral RNA persistence in domestic sheep experimentally infected with Crimean-Congo haemorrhagic fever virus Kosovo Hoti

Distinguishing host responses, extensive viral dissemination and long-term viral RNA persistence in domestic sheep experimentally infected with Crimean-Congo haemorrhagic fever virus Kosovo Hoti

Crimean-Congo haemorrhagic fever orthonairovirus (CCHFV) is a tick-borne, risk group 4 pathogen that often causes a severe haemorrhagic disease in humans (CCHF) with high case fatality rates. The virus is believed to be maintained in a tick-vertebrate-tick ecological cycle involving numerous wild an...

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Bibliographic Details
Main Authors: Hongzhao Li, Mathieu Pinette, Greg Smith, Melissa Goolia, Katherine Handel, Michelle Nebroski, Oliver Lung, Bradley S. Pickering
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Emerging Microbes and Infections
Subjects:
Crimean-Congo haemorrhagic fever virus
Kosovo Hoti
sheep
virus shedding
RNA persistence
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2024.2302103
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https://www.tandfonline.com/doi/10.1080/22221751.2024.2302103

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