Differential effect on different immune subsets of neoadjuvant chemotherapy in patients with TNBC

Differential effect on different immune subsets of neoadjuvant chemotherapy in patients with TNBC

Background Triple-negative breast cancer (TNBC) is the most aggressive form of breast cancer (BC). Due to the absence of targets such as HER2 or hormone receptors, early TNBC is treated with surgery and chemotherapy. Since TNBC is also considered the most immunogenic type of BC with tumor infiltrati...

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Main Authors: Thomas Karn, Frederik Marmé, Christian Jackisch, Barbara Seliger, Chiara Massa, Sibylle Loibl, Volkmar Müller, Carsten Denkert, Andreas Schneeweiss, Claus Hanusch, Jens-Uwe Blohmer, Dirk-Michael Zahm, Marion van Mackelenbergh, Jörg Thomalla, Jens Huober, Christian Schem, Anja Mueller, Elmar Stickeler, Katharina Biehl, Peter A Fasching, Michael Untch, Karsten Weber
Format: Article
Language:English
Published: BMJ Publishing Group 2020-10-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/2/e001261.full
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https://jitc.bmj.com/content/8/2/e001261.full

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