Analysis of nanomedicine applications for inflammatory bowel disease: structural and temporal dynamics, research hotspots, and emerging trends

BackgroundThe application of nanomedicine in inflammatory bowel disease (IBD) has gained significant attention in the recent years. As the field rapidly evolves, analyzing research trends and identifying research hotpots are essential for guiding future advancements, and a comprehensive bibliometric...

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Main Authors: Hong-Yu Jiang, Bo Shao, Hong-Da Wang, Wen-Qi Zhao, Shao-Hua Ren, Yi-Ni Xu, Tong Liu, Cheng-Lu Sun, Yi-Yi Xiao, Yi-Cheng Li, Qiang Chen, Peng-Yu Zhao, Guang-Mei Yang, Xu Liu, Yu-Fan Ren, Hao Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1523052/full
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author Hong-Yu Jiang
Hong-Yu Jiang
Bo Shao
Bo Shao
Hong-Da Wang
Hong-Da Wang
Wen-Qi Zhao
Shao-Hua Ren
Shao-Hua Ren
Shao-Hua Ren
Yi-Ni Xu
Yi-Ni Xu
Tong Liu
Tong Liu
Cheng-Lu Sun
Cheng-Lu Sun
Yi-Yi Xiao
Yi-Yi Xiao
Yi-Cheng Li
Yi-Cheng Li
Qiang Chen
Qiang Chen
Peng-Yu Zhao
Peng-Yu Zhao
Guang-Mei Yang
Guang-Mei Yang
Xu Liu
Xu Liu
Yu-Fan Ren
Yu-Fan Ren
Hao Wang
Hao Wang
Hao Wang
author_facet Hong-Yu Jiang
Hong-Yu Jiang
Bo Shao
Bo Shao
Hong-Da Wang
Hong-Da Wang
Wen-Qi Zhao
Shao-Hua Ren
Shao-Hua Ren
Shao-Hua Ren
Yi-Ni Xu
Yi-Ni Xu
Tong Liu
Tong Liu
Cheng-Lu Sun
Cheng-Lu Sun
Yi-Yi Xiao
Yi-Yi Xiao
Yi-Cheng Li
Yi-Cheng Li
Qiang Chen
Qiang Chen
Peng-Yu Zhao
Peng-Yu Zhao
Guang-Mei Yang
Guang-Mei Yang
Xu Liu
Xu Liu
Yu-Fan Ren
Yu-Fan Ren
Hao Wang
Hao Wang
Hao Wang
author_sort Hong-Yu Jiang
collection DOAJ
description BackgroundThe application of nanomedicine in inflammatory bowel disease (IBD) has gained significant attention in the recent years. As the field rapidly evolves, analyzing research trends and identifying research hotpots are essential for guiding future advancements, and a comprehensive bibliometric can provide valuable insights.MethodsThe current research focused on publications from 2001 to 2024, and was sourced from the Web of Science Core Collection (WoSCC). CiteSpace and VOSviewer were employed to visualize authors, institutions, countries, co-cited references, and keywords, thereby mapping the intellectual structure and identifying emerging trends in the field.ResultsThe analysis covered 1,518 literature across 447 journals, authored by 9,334 researchers from 5,459 institutions and 287 countries/regions. The global publication numbers exhibited an upward trend, particularly in the last decade, with China leading as the top publishing country and the Chinese Academy of Sciences emerging as the foremost institution. Dr. Xiao Bo is the prominent figure in advanced drug delivery systems. This interdisciplinary field, which spans materials science, pharmacy, and medicine, has seen influential publications mainly concentrated on targeted nanoparticles treatment for IBD. Keyword analysis revealed that current research hotspots include drug delivery, immune cell regulation, antioxidant damage, intestinal microbiota homeostasis, and nanovesicles.ConclusionThis study offers a comprehensive overview of global research landscape, emphasizing the rapid growth and increasing complexity of this field. It identifies key research hotspots and trends, including efforts to enhance the precision, efficacy, and safety of nanomedicine applications. Emerging directions are highlighted as crucial for further progress in this evolving area.
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spelling doaj-art-5a594567cf784e12a433d174b09af4d42025-01-08T06:11:42ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122025-01-011510.3389/fphar.2024.15230521523052Analysis of nanomedicine applications for inflammatory bowel disease: structural and temporal dynamics, research hotspots, and emerging trendsHong-Yu Jiang0Hong-Yu Jiang1Bo Shao2Bo Shao3Hong-Da Wang4Hong-Da Wang5Wen-Qi Zhao6Shao-Hua Ren7Shao-Hua Ren8Shao-Hua Ren9Yi-Ni Xu10Yi-Ni Xu11Tong Liu12Tong Liu13Cheng-Lu Sun14Cheng-Lu Sun15Yi-Yi Xiao16Yi-Yi Xiao17Yi-Cheng Li18Yi-Cheng Li19Qiang Chen20Qiang Chen21Peng-Yu Zhao22Peng-Yu Zhao23Guang-Mei Yang24Guang-Mei Yang25Xu Liu26Xu Liu27Yu-Fan Ren28Yu-Fan Ren29Hao Wang30Hao Wang31Hao Wang32Department of General Surgery, Tianjin Medical University General Hospital, Tianjin, ChinaTianjin General Surgery Institute, Tianjin Medical University General Hospital, Tianjin, ChinaDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, ChinaTianjin General Surgery Institute, Tianjin Medical University General Hospital, Tianjin, ChinaDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, ChinaTianjin General Surgery Institute, Tianjin Medical University General Hospital, Tianjin, ChinaTianjin Key Laboratory of Precise Vascular Reconstruction and Organ Function Repair, Tianjin, ChinaDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, ChinaTianjin General Surgery Institute, Tianjin Medical University General Hospital, Tianjin, ChinaDepartment of General Surgery, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, ChinaDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, ChinaTianjin General Surgery Institute, Tianjin Medical University General Hospital, Tianjin, ChinaDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, ChinaTianjin General Surgery Institute, Tianjin Medical University General Hospital, Tianjin, ChinaDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, ChinaTianjin General Surgery Institute, Tianjin Medical University General Hospital, Tianjin, ChinaDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, ChinaTianjin General Surgery Institute, Tianjin Medical University General Hospital, Tianjin, ChinaDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, ChinaTianjin General Surgery Institute, Tianjin Medical University General Hospital, Tianjin, ChinaDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, ChinaTianjin General Surgery Institute, Tianjin Medical University General Hospital, Tianjin, ChinaDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, ChinaTianjin General Surgery Institute, Tianjin Medical University General Hospital, Tianjin, ChinaDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, ChinaTianjin General Surgery Institute, Tianjin Medical University General Hospital, Tianjin, ChinaDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, ChinaTianjin General Surgery Institute, Tianjin Medical University General Hospital, Tianjin, ChinaDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, ChinaTianjin General Surgery Institute, Tianjin Medical University General Hospital, Tianjin, ChinaDepartment of General Surgery, Tianjin Medical University General Hospital, Tianjin, ChinaTianjin General Surgery Institute, Tianjin Medical University General Hospital, Tianjin, ChinaTianjin Key Laboratory of Precise Vascular Reconstruction and Organ Function Repair, Tianjin, ChinaBackgroundThe application of nanomedicine in inflammatory bowel disease (IBD) has gained significant attention in the recent years. As the field rapidly evolves, analyzing research trends and identifying research hotpots are essential for guiding future advancements, and a comprehensive bibliometric can provide valuable insights.MethodsThe current research focused on publications from 2001 to 2024, and was sourced from the Web of Science Core Collection (WoSCC). CiteSpace and VOSviewer were employed to visualize authors, institutions, countries, co-cited references, and keywords, thereby mapping the intellectual structure and identifying emerging trends in the field.ResultsThe analysis covered 1,518 literature across 447 journals, authored by 9,334 researchers from 5,459 institutions and 287 countries/regions. The global publication numbers exhibited an upward trend, particularly in the last decade, with China leading as the top publishing country and the Chinese Academy of Sciences emerging as the foremost institution. Dr. Xiao Bo is the prominent figure in advanced drug delivery systems. This interdisciplinary field, which spans materials science, pharmacy, and medicine, has seen influential publications mainly concentrated on targeted nanoparticles treatment for IBD. Keyword analysis revealed that current research hotspots include drug delivery, immune cell regulation, antioxidant damage, intestinal microbiota homeostasis, and nanovesicles.ConclusionThis study offers a comprehensive overview of global research landscape, emphasizing the rapid growth and increasing complexity of this field. It identifies key research hotspots and trends, including efforts to enhance the precision, efficacy, and safety of nanomedicine applications. Emerging directions are highlighted as crucial for further progress in this evolving area.https://www.frontiersin.org/articles/10.3389/fphar.2024.1523052/fullbibliometricsnanomedicineinflammatory bowel diseaseresearch trendsemerging frontiers
spellingShingle Hong-Yu Jiang
Hong-Yu Jiang
Bo Shao
Bo Shao
Hong-Da Wang
Hong-Da Wang
Wen-Qi Zhao
Shao-Hua Ren
Shao-Hua Ren
Shao-Hua Ren
Yi-Ni Xu
Yi-Ni Xu
Tong Liu
Tong Liu
Cheng-Lu Sun
Cheng-Lu Sun
Yi-Yi Xiao
Yi-Yi Xiao
Yi-Cheng Li
Yi-Cheng Li
Qiang Chen
Qiang Chen
Peng-Yu Zhao
Peng-Yu Zhao
Guang-Mei Yang
Guang-Mei Yang
Xu Liu
Xu Liu
Yu-Fan Ren
Yu-Fan Ren
Hao Wang
Hao Wang
Hao Wang
Analysis of nanomedicine applications for inflammatory bowel disease: structural and temporal dynamics, research hotspots, and emerging trends
Frontiers in Pharmacology
bibliometrics
nanomedicine
inflammatory bowel disease
research trends
emerging frontiers
title Analysis of nanomedicine applications for inflammatory bowel disease: structural and temporal dynamics, research hotspots, and emerging trends
title_full Analysis of nanomedicine applications for inflammatory bowel disease: structural and temporal dynamics, research hotspots, and emerging trends
title_fullStr Analysis of nanomedicine applications for inflammatory bowel disease: structural and temporal dynamics, research hotspots, and emerging trends
title_full_unstemmed Analysis of nanomedicine applications for inflammatory bowel disease: structural and temporal dynamics, research hotspots, and emerging trends
title_short Analysis of nanomedicine applications for inflammatory bowel disease: structural and temporal dynamics, research hotspots, and emerging trends
title_sort analysis of nanomedicine applications for inflammatory bowel disease structural and temporal dynamics research hotspots and emerging trends
topic bibliometrics
nanomedicine
inflammatory bowel disease
research trends
emerging frontiers
url https://www.frontiersin.org/articles/10.3389/fphar.2024.1523052/full
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