Gallic acid alleviates hippocampus and cerebellum injuries in a rat model of hepatic encephalopathy

Gallic acid alleviates hippocampus and cerebellum injuries in a rat model of hepatic encephalopathy

Abstract Liver cirrhosis leads to portal hypertension and hepatic encephalopathy (HE). Bile duct ligation (BDL) is a valid model for developing HE in animal models. The present study investigated the protective effects of gallic acid (GA) against BDL-induced injuries in male rats. 64 male Wistar rat...

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Bibliographic Details
Main Authors: Leila Jafaripour, Hassan Ahmadvand, Esmaeel Babaeenezhad, Khadijeh Esmaeilpour, Marzieh Maneshian, Hamideh Bashiri, Majid Asadi-Shekaari
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Gallic acid
Hepatic encephalopathy
AMPK
Inflammation
Hippocampus
Cerebellum
Online Access:https://doi.org/10.1038/s41598-025-15524-5
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https://doi.org/10.1038/s41598-025-15524-5

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