Faecalibacterium prausnitzii enhances intestinal IgA response by host-microbe derived inecalcitol in colitis

Faecalibacterium prausnitzii enhances intestinal IgA response by host-microbe derived inecalcitol in colitis

Abstract Background Faecalibacterium prausnitzii plays a crucial role in ulcerative colitis (UC) remission, but its action mechanism is unknown. Here, we aimed to explore the potential mechanisms focusing on the interaction of F. prausnitzii with host immune response and its potential modulation on...

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Bibliographic Details
Main Authors: Wenfei Qin, Nuoming Yin, Binqiang Xu, Qixiang Mei, Yang Fu, Junjie Fan, Yingying Lu, Guangqiang Wang, Lianzhong Ai, Zhanjun Lu, Yue Zeng, Chunlan Huang
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Medicine
Subjects:
Faecalibacterium prausnitzii
Experimental colitis
Immunoglobulin a
Inecalcitol
Online Access:https://doi.org/10.1186/s12916-025-04260-2
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